At first blush a game called “Creationary” may sound a bit anti-science but it is, in fact, just Pictionary with Legos. It costs $34 and is for ages 7-12 and apparently you can build your own die and then pick cards to tell each player what to build. You can make vehicles, buildings, or items from nature (there’s also a nebulous “things” category) and it’s for 3 to 8 players.
UPDATED Lego bricks are included so you won’t have to go scrounging under the couch for the big green board and pull all the small two stud pieces out of the vacuum cleaner if you really intend to get into some serious competition.