Skype has suffered a major service outage that started from approximately 3am PST Thursday.
The issue was serious enough to cause Skype to temporarily disable all downloads of the Skype client.
Skpe has had a very strong record of uptime previously and this outage is a first in recent memory. In comparison Twitter was down intermittently from 7pm PST Wednesday for around 6 hours, a fairy regular occurrence. Skype remained down at the time of writing as at 7:30am PST.