Megite has been getting some attention on the Web 2.0 Workgroup email list as possibly the first company to be able to group blogging conversations as well as Memeorandum (profiles). The site is very rough design-wise, but is grouping things intelligently and seems to be popping popular stuff up to the top fairly quickly.
Memeorandum has redefined how early adopters get and digest their news. While these sites are still young, they will have a disruptive impact on the big guys, soon. Tailrank (profiles), another service in this space, is also doing interesting things, like analyzing user-uploaded OPML files for additional data and including a screen shot of the post/item under discussion.
For additional information on Memeorandum see this interview with Founder Gabe Rivera.